Biomedical physics research
Biomedical physics deals with applications of physics to questions of biology and medicine. It is an interdisciplinary field of science that involves the application of subspecialties of biology, chemistry, physics, mathematics and computer sciences for the growth and development of medical science and healthcare.
My research interests are in experimental soft matter physics and biophysics, including the development of state-of-the-art atomic force microscopy (AFM) techniques for nanomechanical measurements, mechanics and dynamics of nanoconfined liquids, combining AFM and quasi-elastic neutron diffraction to study confined systems, single-molecule force measurements and nanomechanics on live biological cells for fundamental research and to solve biological problems in cancer progression, combining AFM and fluorescence microscopy, computer simulations of biological and confined systems.
YM Huang Laboratory of Computational Biophysics
We are a vibrant computational molecular modeling group. The central goal of our work is to understand the fundamental mechanism of biomolecular recognition and diffusion processes by using theoretical and classical mechanical models. Our research involves the development and application of computational methods to address biologically and medically important problems. We are at the interface of physics, biology, chemistry, pharmacology, and computer science.
Kelly Laboratory for Nanoscale Optics and Membrane Biophysics
In the Kelly Lab, we employ a variety of experimental and computational methods to explore the nanoscale properties of membranes. We focus on developing and employing novel optical methods to reveal the interplay of curvature, lipid phases, single-molecule sorting, and diffusion on cell membranes.
Our research interests include:
- 2D/3D imaging at the nanometer level
- Collective analysis at the single-molecule level
- Single-molecule to ensemble work
- Cytoskeletal organization: deafness and cancer
- Kinetics and mechanical force study for heart failure